What is PDRN? A restorative brightening treatment that doesn't require injections.

PDRN 係咩?唔使打針都做到嘅修復亮白保養

Recently, you've likely heard a lot about PDRN—medical aesthetic clinics say you can get injections, and skincare products claim to contain it. But what exactly is PDRN? Let’s clear it up once and for all.

What is PDRN?

PDRN stands for Polydeoxyribonucleotide. Primarily extracted from salmon DNA, it is a restorative ingredient with a structure very similar to human DNA. Due to its high compatibility, it helps the skin repair itself, addressing signs of damage, dullness, and aging.

What are the benefits of PDRN?

  • Repairs damaged skin: Helps skin affected by UV rays, late nights, and stress return to a healthy state.
  • Brightens skin tone: Improves dullness and uneven skin tone, giving the skin a natural glow.
  • Smooths fine lines: Works with hydration to make dry lines and fine lines less visible.
  • Boosts elasticity: With long-term use, skin feels fuller and more resilient.

Who should use PDRN?

If you fit the following descriptions, PDRN is perfect for you:

  • You are over 28 and starting to notice your skin looks dull or lacks its former glow.
  • You frequently stay up late or work at a computer, and your face often looks tired.
  • You want repair and brightening effects but prefer to avoid invasive procedures.

How to effectively use PDRN?

PDRN is a serum-grade ingredient. It is recommended to use it after cleansing and prepping your skin with a toner. Apply 2–3 drops evenly over your face and gently massage until absorbed; it can be used both morning and night. Remember: repair is cumulative. Use it consistently for 4–6 weeks to see a noticeable difference—don't give up after just two days.

What to look for when choosing PDRN products

The concentration and formulations of PDRN products on the market vary significantly. When choosing, check if the ingredient list explicitly states PDRN, if it’s suited to your skin type (oily or dry), and whether it contains complementary hydrating ingredients—repair and hydration are twins; you need both.


Progean's Pick: PDRN Radiance Boosting Essence ($698/10ml)
A high-efficiency repair essence containing PDRN, focused on improving dullness and smoothing fine lines. Its 10ml concentrated formula requires only 2–3 drops daily. Perfect for those over 28 who are seeking brightening and repair.